Carbamic acid, N-[2-(2-bromoethoxy)ethyl]-, 1,1-dimethylethyl ester
t-boc-N-amido-PEG2-bromide
CAS: 164332-88-1
Molecular Formula: C9H18BrNO3
Carbamic acid, N-[2-(2-bromoethoxy)ethyl]-, 1,1-dimethylethyl ester - Names and Identifiers
Carbamic acid, N-[2-(2-bromoethoxy)ethyl]-, 1,1-dimethylethyl ester - Physico-chemical Properties
| Molecular Formula | C9H18BrNO3 |
| Molar Mass | 268.16 |
| Density | 1.283±0.06 g/cm3(Predicted) |
| Boling Point | 336.6±22.0 °C(Predicted) |
| Storage Condition | Room Temprature |
| Refractive Index | Sealed in dry,Store |
Carbamic acid, N-[2-(2-bromoethoxy)ethyl]-, 1,1-dimethylethyl ester - Road and Synthesis
Bioactive N-Boc-PEG2-bromide is a PROTAC connection bridge, belonging to PEG and Alkyl/ether. N-Boc-PEG2-bromide can be used to synthesize a series of PROTAC molecules. N-Boc-PEG2-bromide is a degradable (cleavable) ADC connection bridge for the synthesis of antibody drug conjugates (ADCs)
Target
CleavablePEGsAlkyl/ether
in vitro studies
PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker.
Last Update：2024-04-09 20:52:54
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Product Name: t-boc-N-amido-PEG2-bromide Visit Supplier Webpage Request for quotation
CAS: 164332-88-1
Tel: 18301782025
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Mobile: 18021002903
QQ: 3008007409
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CAS: 164332-88-1
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
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